Aminoglycoside antibiotics. XV. Chemical conversion of neomycin B to paromomycin I, 6'"-deamino-6'"-hydroxyneomycin B and 6'"-deamino-6'"-hydroxy-paromomycin I.

I-6: IVF in Low Resources Countries

I-6: Azoospermia Factor in Male Infertility

Background The human Y chromosome is essential for human sex determination and male germ cell development and maintenance. In 1996, Vogt et al. identified three recurrently deleted regions in Yq11 termed the azoospermia factor (AZF). The AZF region is subdivided into three non-overlapping sub-regions called AZFa, AZFb and AZFc and microdeletion in these regions is the most important etiology of...

I-6: Remodelling Uterine Spiral Arteries inPregnancy

Background: During the first trimester of pregnancy the uterine spiral arteries that supply blood to the placenta are remodelled, creating heavily dilated conduits lacking maternal vasomotor control. To effect permanent vasodilatation, the internal elastic lamina and medial elastic fibres must be degraded. Failure of remodelling is a key characteristic of the pathological placenta and is though...

Natriuretic properties of [2-p-ethylphenylalanine] deamino-6-carba-oxytocin (Nacartocin) in cats.

Nacartocin, a synthetic analogue of oxytocin, [2-L-p-phenylalanine]deamino-6-carba-oxytocin has a specific natriuretic effect in cats. The doses of 0.05-10 micrograms/kg b.w. (0.05-10 nmols/kg) of Nacartocin applied i.v. caused a several fold increase in the excretion of sodium, while the excretion of kalium was only slightly enhanced.

Folate , B 6 & B 12 Rationale